Serengulam V. Govindan: search on Z-Library

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1

Development of humanized antibodies as cancer therapeutics

Zhengxing Qu, Gary L. Griffiths, William A. Wegener, Chien-Hsing Chang, Serengulam V. Govindan, Ivan D. Horak, Hans J. Hansen, David M. Goldenberg

Journal:

Year:

2005

Language:

english

File:

PDF, 459 KB

english, 2005

2

Carbohydrates engineered at antibody constant domains can be used for site-specific conjugation of drugs and chelates

Zhengxing Qu, Robert M Sharkey, Hans J Hansen, Lisa B Shih, Serengulam V Govindan, Jian Shen, David M Goldenberg, Shui-on Leung

Journal:

Journal of Immunological Methods

Year:

1998

Language:

english

File:

PDF, 394 KB

english, 1998

3

Successful therapy of a human lung cancer xenograft using MAb RS7 labeled with residualizing radioiodine

Rhona Stein, Serengulam V Govindan, Susan Chen, Linda Reed, Heidi Spiegelman, Gary L Griffiths, Hans J Hansen, David M Goldenberg

Journal:

Critical Reviews in Oncology/Hematology

Year:

2001

Language:

english

File:

PDF, 126 KB

english, 2001

4

Designing immunoconjugates for cancer therapy

Govindan, Serengulam V, Goldenberg, David M

Journal:

Expert Opinion on Biological Therapy

Year:

2012

Language:

english

File:

PDF, 528 KB

english, 2012

5

Sacituzumab Govitecan, a Novel Antibody–Drug Conjugate, in Patients With Metastatic Platinum-Resistant Urothelial Carcinoma

Faltas, Bishoy, Goldenberg, David M., Ocean, Allyson J., Govindan, Serengulam V., Wilhelm, Francois, Sharkey, Robert M., Hajdenberg, Julio, Hodes, Gillian, Nanus, David M., Tagawa, Scott T.

Journal:

Clinical Genitourinary Cancer

Year:

2015

Language:

english

File:

PDF, 989 KB

english, 2015

6

Improving the Therapeutic Index in Cancer Therapy by Using Antibody–Drug Conjugates Designed with a Moderately Cytotoxic Drug

Govindan, Serengulam V., Cardillo, Thomas M., Rossi, Edmund A., Trisal, Preeti, McBride, William J., Sharkey, Robert M., Goldenberg, David M.

Journal:

Molecular Pharmaceutics

Year:

2015

Language:

english

File:

PDF, 499 KB

english, 2015

7

Antibody Conjugates of 7-Ethyl-10-hydroxycamptothecin (SN-38) for Targeted Cancer Chemotherapy

Moon, Sung-Ju, Govindan, Serengulam V., Cardillo, Thomas M., D’Souza, Christopher A., Hansen, Hans J., Goldenberg, David M.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 204 KB

english, 2008

8

Deferoxamine as a chelator for 67Ga in the preparation of antibody conjugates

Serengulam V. Govindan, Rosana B. Michel, Gary L. Griffiths, David M. Goldenberg, M. Jules Mattes

Journal:

Nuclear Medicine and Biology

Year:

2005

Language:

english

File:

PDF, 512 KB

english, 2005

9

Use of Galactosylated-Streptavidin as a Clearing Agent with 111 In-Labeled, Biotinylated Antibodies to Enhance Tumor/Non-Tumor Localization Ratios

Govindan, Serengulam V., Griffiths, Gary L., Michel, Rosana B., Andrews, Philip M., Goldenberg, David M., Mattes, M. Jules

Journal:

Cancer Biotherapy & Radiopharmaceuticals

Year:

2002

Language:

english

File:

PDF, 216 KB

english, 2002

10

Thiolations, 99m Tc Labelings, and Animal In Vivo Biodistributions of Divalent Monoclonal Antibody Fragments

Govindan, Serengulam V., Goldenberg, David M., Grebenau, Ruth C., Hansen, Hans J., Griffiths, Gary L.

Journal:

Bioconjugate Chemistry

Year:

1996

Language:

english

File:

PDF, 216 KB

english, 1996

11

Labeling of Monoclonal Antibodies with Diethylenetriaminepentaacetic Acid-Appended Radioiodinated Peptides Containing d -Amino Acids †

Govindan, Serengulam V., Mattes, M. Jules, Stein, Rhona, McBride, Bill J., Karacay, Habibe, Goldenberg, David M., Hansen, Hans J., Griffiths, Gary L.

Journal:

Bioconjugate Chemistry

Year:

1999

Language:

english

File:

PDF, 185 KB

english, 1999

12

Advances in the use of monoclonal antibodies in cancer radiotherapy

Serengulam V Govindan, David M Goldenberg, Hans J Hansen, Gary L Griffiths

Journal:

Pharmaceutical Science & Technology Today

Year:

2000

Language:

english

File:

PDF, 288 KB

english, 2000

13

Prospects and progress of antibody-drug conjugates in solid tumor therapies

Govindan, Serengulam V., Sharkey, Robert M., Goldenberg, David M.

Journal:

Expert Opinion on Biological Therapy

Year:

2016

Language:

english

File:

PDF, 630 KB

english, 2016

14

Trop-2 is a novel target for solid cancer therapy with sacituzumab govitecan (IMMU-132), an antibody-drug conjugate (ADC)*

Goldenberg, David M., Cardillo, Thomas M., Govindan, Serengulam V., Rossi, Edmund A., Sharkey, Robert M.

Journal:

Year:

2015

Language:

english

File:

PDF, 5.11 MB

english, 2015

15

Selective and concentrated accretion of SN-38 with a CEACAM5-targeting antibody-drug conjugate (ADC), labetuzumab govitecan (IMMU-130)

Sharkey, Robert M., Govindan, Serengulam V., Cardillo, Thomas M., Donnell, Jennifer, Xia, Jing, Rossi, Edmund A, Chang, Chien-Hsing, Goldenberg, David M.

Journal:

Molecular Cancer Therapeutics

Year:

2017

Language:

english

File:

PDF, 547 KB

english, 2017

16

IMMU-140, a novel SN-38-antibody-drug conjugate targeting HLA-DR, mediates dual cytotoxic effects in hematological cancers and malignant melanoma

Cardillo, Thomas M., Govindan, Serengulam V., Zalath, Maria B., Rossi, Diane L, Wang, Yang, Chang, Chien-Hsing, Goldenberg, David M.

Journal:

Molecular Cancer Therapeutics

Year:

2017

Language:

english

File:

PDF, 3.46 MB

english, 2017

17

The advantage of residualizing radiolabels for targeting B-cell lymphomas with a radiolabeled anti-CD22 monoclonal antibody

M. Jules Mattes, Lisa B. Shih, Serengulam V. Govindan, Robert M. Sharkey, Gaik Lin Ong, Hong Xuan, David M. Goldenberg

Journal:

International Journal of Cancer

Year:

1997

Language:

english

File:

PDF, 104 KB

english, 1997

18

Heteroatom cyclopentene annulation. Synthesis of guaiane ring system

Hudlicky, Tomas, Govindan, Serengulam V., Frazier, James O.

Journal:

Journal of Organic Chemistry

Year:

1985

Language:

english

File:

PDF, 818 KB

english, 1985

19

Sacituzumab Govitecan (IMMU-132), an Anti-Trop-2/SN-38 Antibody–Drug Conjugate: Characterization and Efficacy in Pancreatic, Gastric, and Other Cancers

Cardillo, Thomas M., Govindan, Serengulam V., Sharkey, Robert M., Trisal, Preeti, Arrojo, Roberto, Liu, Donglin, Rossi, Edmund A., Chang, Chien-Hsing, Goldenberg, David M.

Journal:

Bioconjugate Chemistry

Year:

2015

Language:

english

File:

PDF, 1.40 MB

english, 2015

20

Development of a Streptavidin−Anti-Carcinoembryonic Antigen Antibody, Radiolabeled Biotin Pretargeting Method for Radioimmunotherapy of Colorectal Cancer. Reagent Development †

Karacay, Habibe, Sharkey, Robert M., Govindan, Serengulam V., McBride, William J., Goldenberg, David M., Hansen, Hans J., Griffiths, Gary L.

Journal:

Bioconjugate Chemistry

Year:

1997

Language:

english

File:

PDF, 210 KB

english, 1997

21

Sacituzumab Govitecan (IMMU-132) in treatment-resistant uterine serous carcinoma: A case report

Han, Chanhee, Bellone, Stefania, Schwartz, Peter E., Govindan, Serengulam V., Sharkey, Robert M., Goldenberg, David M., Santin, Alessandro D.

Journal:

Gynecologic Oncology Reports

Year:

2018

Language:

english

File:

PDF, 1.17 MB

english, 2018

22

Cytotoxicity with Auger electron-emitting radionuclides delivered by antibodies

Gary L. Griffiths, Serengulam V. Govindan, George Sgouros, Gaik Lin Ong, David M. Goldenberg, M. Jules Mattes

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 132 KB

english, 1999

23

New Antibody Conjugates in Cancer Therapy

Govindan, Serengulam V., Goldenberg, David M.

Journal:

The Scientific World JOURNAL

Year:

2010

Language:

english

File:

PDF, 1.59 MB

english, 2010

24

90 Yttrium-Labeled Complementarity-Determining-Region-Grafted Monoclonal Antibodies for Radioimmunotherapy: Radiolabeling and Animal Biodistribution Studies †

Govindan, Serengulam V., Shih, Lisa B., Goldenberg, David M., Sharkey, Robert M., Karacay, Habibe, Donnelly, Joseph E., Losman, Michele J., Hansen, Hans J., Griffiths, Gary L.

Journal:

Bioconjugate Chemistry

Year:

1998

Language:

english

File:

PDF, 140 KB

english, 1998

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